x Gergely J Szollosi
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My name is Gergely Szöllősi and I currently head the "Lendület" Evolutionary Genomics Research Group of the Hungarian Academy of Sciences and the ERC "GENECLOCKS" Research Group hosted at The Institute of Physics at Eötvös University in Budapest. Until 2013 July I was a a Marie Curie Fellow at the Bioinformatics. Phylogenetics and Evolutionary Genomics Group at LBBE in Lyon. For more details about me and my career to date see my CV and here.



Congratulations to Edu for his first publication as a postdoc! A strong start with a Nature paper: "Divergent genomic trajectories predate the origin of animals and fungi". See also the University news piece in English and Hungarian!

The large genetic differences between modern animals and fungi are the outcome of two contrasting trajectories of genetic changes that preceded the origin of both groups.

Our new paper "Trade-off between reducing mutational accumulation and increasing commitment to differentiation determines tissue organization" is out in Nature Communcations!

 Minimal generic model of hierarchically differentiating tissues and corresponding cell lineage trees.


Our new paper "A rooted phylogeny resolves early bacterial evolution" is out in Science! A rooted phylogeny of Bacteria. The reconciliation of bacterial gene phylogenies places the root between the major clades of Gracilicutes (including Proteobacteria and Bacteroidota) and Terrabacteria (including Firmicutes and Cyanobacteria). On the basis of this hypothesis, ancestral genome reconstruction predicts that the last bacterial common ancestor (LBCA) was a complex, double-membraned cell and that, on average, two-thirds of gene transmissions have been vertically inherited along this rooted tree.


We are looking for postdocs to work on the origin of eukaryotes in a project funded jointly by the Simons and Moore Foundations, please click (Moore postdoc) for deatils!

We are looking for postdocs to work on the ERC "GENECLOCKS" project! Please click (postdocs) for deatils

Two new papers out in MBE!

Schrempf, Lartillott, Szöllősi: "Scalable empirical mixture models that account for across-site compositional heterogeneity

Morel, Kuzlov, Stamatakis, Szöllősi: "GeneRax: A Tool for Species-Tree-Aware Maximum Likelihood-Based Gene Family Tree Inference under Gene Duplication, Transfer, and Loss "

Our new paper "Mutants go extinct under a threshold proliferation advantage." is out in PNAS. More on somatic evolution coming soon!

 Minimal generic model of hierarchically differentiating tissues and corresponding cell lineage trees.


Our new paper "Phylogenomics provides robust support for a two-domains tree of life" (pdf) is out in Natrue Ecology and Evolution. Evidence that the 3D tree is an artefact of long-branch attraction.

We have two exciting new phylogenetic methods out on github (and BioRχiv)! "GeneRax" developed with Benoit Morel and the guys at "Exelixis lab" allows you to infer species tree aware gene trees straigth from the alignment and "EDCluster" a new, scalable method for finding empirical distribution mixture models (which can be used with IQ-TREE, Phylobayes, and RevBayes and out perform C10-C60), developed with Domink Schrempf and Nicolas Lartillot.


Our paper "Gene transfers can date the tree of life" is out in Nature Ecology and Evolution online and was recently covered in Quanta Magazine: Chronological Clues to Life's Early History Lurk in Gene Transfers.


We are looking for postdocs and PhD students to work on the ERC "GENECLOCKS" project! Please click (postdocs) or (PhDs) for deatils Our new paper "Integrative modeling of gene and genome evolution roots the archaeal tree of life" is out in PNAS! (Open Acces) I am looking for a postdoc to work on Physics of Cancer! Please click here for details. Our new paper "How long does Wolbachia remain onboard?" was recently published in MBE. (link to pdf) Our new paper "Hierarchical tissue organization as a general mechanism to limit the accumulation of somatic mutations" is to apper in Nature Communications. (Open Acces)


Our review "Horizontal Gene Transfer and the History of Life" is to appear in Cold Spring Harbor Perspectives in Biology. (link to pdf)

Our paper describing extensive Lateral Gene Transfer among Fungi in the Philisophical Transactions special issue "Eukaryotic origins: progress and challenges" is now online. (Open Acces)

and before ..

I had the opportunity to give the first in a series of three talks in phyloseminar.org's Mini-course on genome-scale phylogeny.

Gergely J. Sz÷ll§si
Szollosi GJ